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1976- The Founding
The Maine Cancer Foundation was established in 1976, the result of a gift received from a person whose wife had died of cancer. The patients’ family and others wanted to establish a cancer research foundation dedicated to Maine people such that all funds raised within the state would stay in Maine.

1980's - The Early Years
For the first ten years or so, the Foundation received small memorial gifts. The Board of Directors would meet periodically and decide how much funding to award in grants. Funds were limited. Support of significant research, particularly a multi-year commitment to support research was not possible. Some years the level of funding that the Foundation could provide was minimal and no proposals were received. Nevertheless, the foundation continued its work.

Since its beginning, Maine Cancer Foundation has underwritten "Discovery Weekend." This weekend retreat was created to fill a gap in the unmet needs of patients for emotional and spiritual support. The weekend retreats focus on integrating medicine, spirituality, and communication skills in the lives of people with cancer. Three weekends have been held each year for the past twenty-three years. A dedicated volunteer staff of physicians, psychologists and social workers facilitate the weekend program. Hundreds of cancer patients with their husband/wife or other loved one have benefited. The Foundation provides financial support to anyone who wants to attend and may not be able to afford to.

During the 1980’s science and the world of molecular biology was undergoing rapid development. All cancers are diseases if unregulated genes. Physicians on the board of MCF were anxious that cancer patients within the state of Maine benefit from whatever scientific applications this science had to offer. Because of the rapid development of this branch of science, it was determined that the foundation could and should play an active role in the professional education of physicians, nurses and others in the application of DNA based science. The Foundations name was changed to reflect the inclusion of education as part of the mission hence, the Maine Cancer Research and Education Foundation.

1990's - Opportunity
In the early 1990's Dr. Ronald Carroll, a medical oncologist at Maine Center for Cancer Medicine, who had been on the Foundation board since its inception, became its next President succeeding Roger Castonguay. Dr. Carroll felt that the Foundation had a major role to play in the fight against cancer in the state. As a result of a successful proposal to the Davis Foundation, the first full time director was hired in 1992 and a small office provided in Portland.

As assets grew, the Foundation created and presented a twelve-hour symposium on the fundamentals of DNA science, as it applied to cancer, to physicians in the state through several hospitals. In addition, the Foundation presented symposia at the University of Maine School of Law in an effort to increase awareness among lawyers and law makers to issues of confidentiality as they relate to genetic information, to patient care, the law, and the potential for genetic based discrimination against patients. The same fundamental information was also presented to the public through Senior College at the University of Southern Maine.

The Foundation has also developed fund raising events. A Road Race was held for three years, 1995-98, followed be a Golf Tournament in 1999 and planned for 2000. MCF joined the Community Health Charities appeal. Grant proposals were written for specific needs. Several significant bequests were received continuing the organizations growth.